Description

2-Chloro-3-(2-Fluorophenyl)-1-Propene is a versatile halogenated aromatic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both chloro and fluoro substituents on a propenylbenzene scaffold, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, or organic electronic materials with unique optical or electrical properties.
• Chemical Intermediate: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and other catalytic transformations to introduce the 2-fluorophenylpropene moiety into more complex structures.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, exploring new synthetic pathways and reaction mechanisms involving halogenated olefins.

Basic Information

Product Name	2-Chloro-3-(2-Fluorophenyl)-1-Propene
CAS No.	731772-93-3
Molecular Formula	C9H8ClF
Molecular Weight	170.61 g/mol
Synonyms	1-Propene, 2-chloro-3-(2-fluorophenyl)-; 2-Chloro-3-(2-fluorophenyl)prop-1-ene; (2-Fluorophenyl)allyl chloride; 2-Fluorocinnamyl chloride; 3-(2-Fluorophenyl)-2-chloroprop-1-ene; 2-Chloro-1-(2-fluorophenyl)-2-propene; Allyl chloride, 2-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(2-Fluorophenyl)-1-Propene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.