Description

2-Bromo-3-(3-Cyanophenyl)-1-Propene is a versatile brominated aromatic intermediate featuring both a reactive bromoalkene group and a cyano substituent. This unique bifunctional structure makes it a valuable building block for the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients and advanced materials. The compound, with CAS number 731772-71-7, is supplied to meet the stringent purity requirements of modern chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or as kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen and nitrile functionality.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphine ligands or metal-organic frameworks (MOFs).
• Material Science Research: Building block for polymers and advanced organic electronic materials due to its conjugated system potential.
• Cross-Coupling Reactions: The bromoalkene moiety is amenable to various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for carbon-carbon bond formation.
• Chemical Biology Probes: Used to create tagged molecules or activity-based probes for studying biological pathways.

Basic Information

Item	Detail
Product Name	2-Bromo-3-(3-Cyanophenyl)-1-Propene
CAS No.	731772-71-7
Molecular Formula	C10H8BrN
Molecular Weight	222.08 g/mol
Synonyms	3-(3-Cyanophenyl)-2-bromoprop-1-ene; 1-(2-Bromoallyl)-3-cyanobenzene; 2-Bromo-3-(3-cyanophenyl)prop-1-ene; m-Cyanophenyl-2-bromoallyl; (3-Cyanophenyl)-2-bromoallyl; 2-Bromoallyl-3-cyanobenzene; 3-(2-Bromoallyl)benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-(3-Cyanophenyl)-1-Propene is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation, to ensure compliance with industry standards for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data (NMR, IR, MS) are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.