Description

L-2,5-Dimethoxyphenylalanine is a non-natural, chiral amino acid derivative featuring methoxy substituents on the aromatic ring. This compound is a critical chiral building block in organic synthesis, valued for its role in constructing complex molecules with defined stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate modified phenylalanine residues, altering peptide stability, lipophilicity, and receptor binding profiles.
• Asymmetric Synthesis: Serves as a starting material or auxiliary in catalytic asymmetric reactions to induce chirality in target molecules.
• Chemical Biology & Proteomics: Employed as a molecular probe or a building block for synthesizing activity-based probes to study enzyme function and protein-protein interactions.
• Material Science Research: Investigated for the creation of novel chiral polymers, supramolecular assemblies, and functional organic materials.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	L-2,5-Dimethoxyphenylalanine
CAS No.	730927-12-5
Molecular Formula	C11H15NO5
Molecular Weight	241.24 g/mol
Synonyms	(S)-2-Amino-3-(2,5-dimethoxyphenyl)propanoic acid; L-2,5-Dimethoxy-Phe; H-2,5-Dimethoxy-Phe-OH; (S)-2,5-Dimethoxyphenylalanine; 2,5-Dimethoxy-L-phenylalanine; Fmoc-2,5-Dimethoxy-L-phenylalanine (precursor); 730927-12-5; 2,5-Dimethoxy-L-Phe
EINECS	Contact for details

Quality Control

Our L-2,5-Dimethoxyphenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) specifying identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.