Description

Alanine, n-(1-Oxo-2-Propenyl)-, Methyl Ester (9Ci) is a specialized N-acylated amino acid derivative, serving as a versatile building block in advanced organic synthesis. This compound is valued for its reactive acryloyl group and ester functionality, enabling its use in the creation of complex molecules and functional materials. It is primarily required by research institutions and industrial R&D departments focused on pharmaceutical development, peptide chemistry, and the synthesis of novel polymers or biochemical probes.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs) and prodrugs, particularly in peptide mimetics and targeted drug conjugates.
• Peptide Chemistry Research: Used as a modified amino acid derivative in solid-phase peptide synthesis (SPPS) to introduce specific properties or reactive handles into peptide chains.
• Bioconjugation & Probe Synthesis: The acryloyl moiety allows for Michael addition reactions, making it suitable for labeling biomolecules, creating fluorescent probes, or developing diagnostic agents.
• Polymer Science: Acts as a functional monomer or cross-linking agent in the synthesis of specialty polymers, hydrogels, or smart materials with tailored properties.
• Chemical Biology Tool: Employed in studying enzyme mechanisms or protein interactions by serving as an inhibitor or activity-based probe precursor.
• Agrochemical Research: Potential intermediate in the synthesis of novel herbicides, fungicides, or plant growth regulators with enhanced specificity.

Basic Information

Product Name	Alanine, n-(1-Oxo-2-Propenyl)-, Methyl Ester (9Ci)
CAS No.	728947-51-1
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	N-Acryloyl-L-alanine methyl ester; Methyl N-acryloylalaninate; (2S)-2-(Prop-2-enoylamino)propanoic acid methyl ester; L-Alanine, N-(1-oxo-2-propenyl)-, methyl ester; N-Acryloylalanine methyl ester; Acryloyl-L-alanine methyl ester; Methyl (S)-2-acrylamidopropanoate
EINECS	Contact for details

Quality Control

Our Alanine, n-(1-Oxo-2-Propenyl)-, Methyl Ester (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.