Description

trans-2-Amino-4-cyclohexene-1-carboxamide is a high-purity, functionalized cyclohexene derivative serving as a versatile chiral building block in advanced organic synthesis. This compound is valued for its rigid cyclic structure and bifunctional amino-amide groups, enabling precise molecular construction. It is primarily sought by research chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring constrained cyclic scaffolds.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and herbicides, leveraging its structural features for bioactivity.
• Organocatalyst Precursor: Serves as a starting material for the development of novel asymmetric organocatalysts used in enantioselective synthesis.
• Ligand Synthesis: Employed in the preparation of specialized chelating ligands for metal-catalyzed reactions and coordination chemistry.
• Peptidomimetics & Conformationally Restricted Analogs: Integral for creating peptide mimics and rigid analogs in medicinal chemistry programs to enhance metabolic stability and receptor selectivity.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis and chemical biology research.

Basic Information

Product Name	trans-2-Amino-4-cyclohexene-1-carboxamide
CAS No.	727411-24-7
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	(1R,2S,4S)-2-Amino-4-cyclohexene-1-carboxamide; (1S,2R,4R)-2-Amino-4-cyclohexene-1-carboxamide; trans-2-Amino-1-carbamoyl-4-cyclohexene; 4-Cyclohexene-1-carboxamide, 2-amino-, (1R,2S,4S)-rel-; 2-Amino-4-cyclohexenecarboxamide
EINECS	Contact for details

Quality Control

Our trans-2-Amino-4-cyclohexene-1-carboxamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.