Description

5-(2-Hydroxy-Benzoyl)-2-Oxo-1-Thiazol-2-Yl-1,2-Dihydro-Pyridine-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. Research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries need this precise chemical for creating new compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the research and development of new drug candidates, especially for central nervous system (CNS) or anti-infective therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, or insecticides, leveraging its unique thiazole and pyridine motifs.
• Chemical Biology Probe Development: Acts as a scaffold for creating molecular probes to study enzyme function or protein-protein interactions in biological systems.
• Material Science Research: Investigated as a potential monomer or additive for creating specialty polymers with specific optical or electronic properties.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	5-(2-Hydroxy-Benzoyl)-2-Oxo-1-Thiazol-2-Yl-1,2-Dihydro-Pyridine-3-Carbonitrile
CAS No.	725717-42-0
Molecular Formula	C₁₆H₉N₃O₃S
Molecular Weight	323.33 g/mol
Synonyms	5-(2-Hydroxybenzoyl)-2-oxo-1-(thiazol-2-yl)-1,2-dihydropyridine-3-carbonitrile; 1-(1,3-Thiazol-2-yl)-5-(2-hydroxybenzoyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile; 725717-42-0; 5-(2-Hydroxy-benzoyl)-2-oxo-1-thiazol-2-yl-1,2-dihydro-pyridine-3-carbonitrile; 3-Cyano-5-(2-hydroxybenzoyl)-1-(2-thiazolyl)-2(1H)-pyridinone
EINECS	Contact for details

Quality Control

Our production of 5-(2-Hydroxy-Benzoyl)-2-Oxo-1-Thiazol-2-Yl-1,2-Dihydro-Pyridine-3-Carbonitrile adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.