Description

2-Iodo-5-Methoxybenzonitrile is a versatile halogenated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an iodine substituent and a methoxy group, makes it a valuable precursor for constructing complex molecules via cross-coupling reactions and functional group transformations. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used as a building block for creating advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for the synthesis of specialized liquid crystals, organic semiconductors, and advanced polymers.
• Cross-Coupling Reactions: The iodine atom is an excellent handle for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Used in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological systems and pathways.

Basic Information

Item	Details
Product Name	2-Iodo-5-Methoxybenzonitrile
CAS No.	725715-08-2
Molecular Formula	C8H6INO
Molecular Weight	259.05 g/mol
Synonyms	5-Methoxy-2-iodobenzonitrile; 2-Iodo-5-methoxybenzonitrile; 2-Cyano-4-iodoanisole; 4-Iodo-2-methoxybenzonitrile; Benzonitrile, 2-iodo-5-methoxy-; 2-Methoxy-5-iodobenzonitrile; 5-Iodo-2-methoxybenzonitrile; 2-Iodo-5-methoxy-benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Iodo-5-Methoxybenzonitrile is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and GC-MS for impurity profiling, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.