Description

(2-Hydroxyadamant-2-Yl)Acetonitrile is a high-value, functionalized adamantane derivative that serves as a critical building block in advanced organic synthesis. Its unique rigid polycyclic structure combined with reactive nitrile and hydroxyl groups makes it a versatile intermediate for creating complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies, leveraging the adamantane scaffold's lipophilicity and metabolic stability.
• Advanced Material Synthesis: Used in the development of high-performance polymers, resins, and coatings where the adamantane core imparts enhanced thermal stability, rigidity, and chemical resistance.
• Ligand and Catalyst Development: Serves as a backbone for constructing sophisticated ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Intermediate in creating new active ingredients with improved environmental profiles and efficacy.
• Academic & Industrial R&D: A valuable tool for synthetic chemists exploring new reaction pathways and constructing complex, three-dimensional molecules.

Basic Information

Product Name	(2-Hydroxyadamant-2-Yl)Acetonitrile
CAS No.	725246-77-5
Molecular Formula	C12H17NO
Molecular Weight	191.27 g/mol
Synonyms	2-(2-Hydroxyadamantan-2-yl)acetonitrile; 2-(2-Hydroxy-2-adamantyl)acetonitrile; Adamantane-2-acetonitrile, 2-hydroxy-; 2-(2-Hydroxytricyclo[3.3.1.1³,⁷]decan-2-yl)acetonitrile; 2-(2-Hydroxyadamantyl)ethanenitrile
EINECS	Contact for details

Quality Control

Every batch of (2-Hydroxyadamant-2-Yl)Acetonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.