Description

3,3,4,4,4-Pentafluoro-2-Hydroxy-2-Methylbutyric Acid Methyl Ester is a high-value fluorinated building block and intermediate characterized by its unique pentafluoroalkyl and hydroxy ester functionalities. This compound is critical for introducing fluorine atoms into target molecules, thereby enhancing their metabolic stability, lipophilicity, and binding affinity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by material scientists for creating specialty polymers and surface modifiers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorine substitution improves efficacy and environmental profile.
• Advanced Material Precursor: Serves as a monomer or modifier for synthesizing fluoropolymers with enhanced chemical resistance, low surface energy, and thermal stability.
• Liquid Crystal & Electronic Chemicals: Employed in the synthesis of fluorinated components for display technologies and dielectric materials.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex molecules via reactions at the hydroxy or ester groups.
• Surface Active Agent Intermediate: Basis for creating fluorinated surfactants and coatings with oil- and water-repellent properties.

Basic Information

Product Name	3,3,4,4,4-Pentafluoro-2-Hydroxy-2-Methylbutyric Acid Methyl Ester
CAS No.	723294-73-3
Molecular Formula	C7H7F5O3
Molecular Weight	234.12 g/mol
Synonyms	Methyl 3,3,4,4,4-pentafluoro-2-hydroxy-2-methylbutanoate; 2-Hydroxy-2-methyl-3,3,4,4,4-pentafluorobutanoic acid methyl ester; 3,3,4,4,4-Pentafluoro-2-hydroxy-2-methylbutyric acid methyl ester; Pentafluoro-2-hydroxy-2-methylbutyric acid methyl ester; Methyl pentafluorohydroxy methylbutyrate; 723294-73-3; MFCD22586667
EINECS	Contact for details

Quality Control

Our production of 3,3,4,4,4-Pentafluoro-2-Hydroxy-2-Methylbutyric Acid Methyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting critical parameters such as assay and impurity profiles. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0% Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.