Description

Ferumoxytol is a superparamagnetic iron oxide nanoparticle coated with a carbohydrate shell, designed for intravenous administration. This advanced material is critical for its utility as a contrast agent in magnetic resonance imaging (MRI), offering significant advantages in diagnostic clarity and patient safety. It is primarily required by pharmaceutical manufacturers, advanced medical research institutions, and diagnostic imaging centers developing and utilizing next-generation imaging solutions. Ferumoxytol CAS NO 722492-56-0 represents a key component in modern theranostic and biomedical applications.

Application

• MRI Contrast Agent: Used as an ultrasmall superparamagnetic iron oxide (USPIO) contrast agent for enhanced magnetic resonance imaging of the liver, spleen, and lymph nodes.
• Iron Replacement Therapy: Serves as an intravenous iron replacement product for the treatment of iron deficiency anemia in adult patients with chronic kidney disease.
• Biomedical Research: Employed in preclinical and clinical research for studying macrophage activity, inflammatory diseases, and cancer metastasis via MRI tracking.
• Cell Labeling & Tracking: Utilized for in vitro and in vivo labeling and non-invasive tracking of stem cells and other therapeutic cells.
• Drug Delivery Platform: Investigated as a nanocarrier platform for targeted drug delivery in oncology and other therapeutic areas.
• Theranostic Applications: Integral to developing theranostic agents that combine diagnostic imaging and therapeutic functions.

Basic Information

Product Name	Ferumoxytol
CAS No.	722492-56-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Feraheme; Code 7228; Ferumoxytol Non-Stoichiometric Magnetite; Superparamagnetic Iron Oxide Nanoparticle (SPION); USPIO; Ferumoxytol-coated Iron Oxide; Nanomag®-D-spio (related); Carboxydextran-coated Iron Oxide; Feruglose (related class).
EINECS	Contact for details

Quality Control

Our Ferumoxytol is manufactured under strict quality systems. Each batch is subjected to rigorous analytical testing to ensure it meets stringent specifications for pharmaceutical and research use, including particle size distribution, iron content, and endotoxin levels. Certificates of Analysis (COA) are provided, detailing compliance with relevant internal specifications. We support compliance with cGMP and other major pharmacopeial standards as required.

Storage

Preserve in the original, unopened vial or in a tightly closed container as supplied. Store at controlled room temperature, typically between 15°C and 25°C (59°F and 77°F). This product is strictly light-sensitive (protect from all light exposure) and easily oxidized (store under inert atmosphere). Do not freeze. Keep the container tightly sealed in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	Dark brown to black colloidal suspension
Identification (IR)	Conforms
Particle Size (DLS)	17 - 31 nm
Iron Content (Assay)	30 mg/mL
pH	6.0 - 8.0
Endotoxins (LAL)	< 0.5 EU/mg Fe
Sterility	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.