Description

Desferrithiocin is a potent, low-molecular-weight iron chelator belonging to the hydroxypyridinone class of compounds. Its primary value lies in its high affinity and selectivity for ferric iron (Fe³⁺), making it a critical tool for managing iron overload in biological systems. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for investigating novel therapeutic agents for conditions like thalassemia and hemochromatosis.

Application

• Pharmaceutical Research & Development: As a lead compound or reference standard in the development of new iron chelation therapies.
• Biochemical Research: Used in laboratory studies to specifically sequester iron and investigate its role in oxidative stress, cell signaling, and disease pathology.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in analytical laboratories.
• Mechanistic Studies: Employed to probe iron-dependent enzymatic processes and metabolic pathways in vitro and in vivo.
• Contrast Agent Research: Investigated for potential applications in the development of iron-sensitive magnetic resonance imaging (MRI) contrast agents.

Basic Information

Product Name	Desferrithiocin
CAS No.	105635-69-6
Molecular Formula	C₁₃H₁₁NO₃S
Molecular Weight	261.30 g/mol
Synonyms	Desferrithiocin; DFT; 2-(3-Hydroxy-2-pyridinyl)-4-methyl-4-thiazolinecarboxylic acid; 4-Methyl-2-(3-hydroxypyridin-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid; LICN-2.1; NSC 696174; 2-(3-Hydroxy-2-pyridyl)-4-methyl-δ²-thiazoline-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our Desferrithiocin is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing desiccated under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.