Description

Deferasirox Isopropyl Ester is a key pharmaceutical intermediate and chemical building block. This compound is primarily valued for its role in the synthesis of Deferasirox, an important iron chelator used in the treatment of chronic iron overload. It is essential for manufacturers in the pharmaceutical and fine chemical sectors who require high-purity intermediates for active pharmaceutical ingredient (API) production. The compound's specific ester structure offers advantages in synthesis and purification processes.

Application

• Pharmaceutical Intermediate: Critical precursor in the multi-step synthesis of the active pharmaceutical ingredient (API) Deferasirox.
• Research & Development: Used in medicinal chemistry research for developing novel iron chelators and related therapeutic agents.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex organic molecules in laboratory and pilot-scale production.
• Process Chemistry: Employed in optimizing and scaling up manufacturing routes for Deferasirox and its analogs.

Basic Information

Item	Details
Product Name	Deferasirox Isopropyl Ester
CAS No.	1266741-29-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid Isopropyl Ester; Deferasirox Isopropyl Ester; Isopropyl 4-[3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoate; Deferasirox IPA Ester; EXJADE Intermediate Ester; ICL670 Isopropyl Ester
EINECS	Contact for details

Quality Control

Our Deferasirox Isopropyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that detail specifications such as assay, related substances, and residual solvents, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.