Description

Deferoxamine Mesylate is a high-purity iron-chelating agent, essential for the treatment of acute iron intoxication and chronic iron overload conditions. Its primary value lies in its high affinity for ferric iron, forming a stable, water-soluble complex that is readily excreted, thereby preventing cellular damage. This critical pharmaceutical active is indispensable for manufacturers in the pharmaceutical and biotechnology sectors, particularly for producing injectable formulations and diagnostic kits.

Application

• Pharmaceutical Active Ingredient: Primary use in the formulation of injectable drugs for the treatment of iron poisoning and transfusion-related hemosiderosis.
• Biochemical Research: Used as a specific chelator in cell culture and laboratory experiments to study iron metabolism, oxidative stress, and metal-dependent enzyme functions.
• Diagnostic Reagents: A key component in diagnostic kits and assays designed to measure serum iron levels or assess iron-binding capacity.
• Veterinary Medicine: Employed in veterinary practices for treating iron overload in animals, particularly in cases of accidental ingestion.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method validation in pharmaceutical laboratories.

Basic Information

Product Name	Deferoxamine Mesylate
CAS No.	138-14-7
Molecular Formula	C26H52N6O11 • CH4O3S
Molecular Weight	656.79 g/mol
Synonyms	Deferoxamine Methanesulfonate; Desferrioxamine Mesylate; Desferal; DFOM; N'-[5-[Acetyl(hydroxy)amino]pentyl]-N-[5-[[4-[[5-(acetyl-hydroxyamino)pentyl]amino]-4-oxobutanoyl]hydroxyamino]pentyl]-N-hydroxysuccinamide Methanesulfonate; Deferoxamine B Mesylate; CI-679; NSC-527604
EINECS	205-311-7

Quality Control

Our Deferoxamine Mesylate is manufactured under strict quality systems, targeting compliance with pharmaceutical-grade standards. Each batch undergoes comprehensive analytical testing, including identification, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results against established specifications is provided with every shipment to ensure full traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Bacterial Endotoxins	< 5.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.