Description

Epoetin Alfa CAS NO 113427-24-0 is a recombinant human erythropoietin, a glycoprotein hormone essential for stimulating red blood cell production. This product is critical for therapeutic applications, offering a reliable and consistent biological response. It is primarily required by the pharmaceutical and biotechnology industries for the formulation of treatments for anemia associated with chronic kidney disease, chemotherapy, and other clinical conditions.

Application

• Pharmaceutical Formulations: Primary active ingredient in injectable therapeutics for anemia management.
• Chronic Kidney Disease (CKD): Treatment of anemia in patients with CKD, including those on dialysis.
• Oncology Supportive Care: Management of chemotherapy-induced anemia in cancer patients.
• Surgical Pre-treatment: Used to increase hemoglobin levels and reduce the need for blood transfusions prior to major surgery.
• Research & Development: Critical reference standard and reagent in hematology, oncology, and nephrology research.
• Biosimilar Development: Serves as a key comparator in the development and analytical characterization of biosimilar products.

Basic Information

Product Name	Epoetin Alfa
CAS No.	113427-24-0
Molecular Formula	C809H1301N229O240S5
Molecular Weight	~18,000 Da (Glycosylated form)
Synonyms	Epoetin Alfa; Recombinant Human Erythropoietin; rhEPO; Erythropoietin; EPO; Epogen® (Trade Name); Procrit® (Trade Name); Eprex® (Trade Name)
EINECS	Contact for details

Quality Control

Our Epoetin Alfa is manufactured under strict quality systems. Each batch is subjected to a comprehensive battery of tests including identity, purity, potency, and biological activity to ensure it meets stringent pharmaceutical standards. Certificates of Analysis (COA) detailing specifications such as specific activity, isoform profile, and endotoxin levels are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. Do not freeze. This product is hygroscopic (moisture-sensitive) and must be handled under controlled conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder or clear solution
Identification (HPLC/Peptide Mapping)	Conforms to reference standard
Purity (SDS-PAGE/RP-HPLC)	≥ 98.0%
Specific Activity	≥ 1.0 x 10^5 IU/mg
Protein Content (UV)	As per COA
Isoform Profile (IEF)	Conforms to reference standard
Endotoxins (LAL)	< 2.0 EU/mg
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.