Description

3-Buten-2-One, 1-Fluoro-4-Phenyl- is a specialized fluorinated organic building block of significant interest in advanced synthetic chemistry. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where the introduction of a fluorine atom can dramatically alter biological activity and metabolic stability. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine moiety enhances efficacy and environmental persistence.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Research: Employed in academic and industrial R&D for studying fluorination reactions and developing new synthetic methodologies.
• Ligand and Catalyst Development: Useful for creating novel fluorinated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Buten-2-One, 1-Fluoro-4-Phenyl-
CAS No.	719279-48-8
Molecular Formula	C10H9FO
Molecular Weight	164.18 g/mol
Synonyms	1-Fluoro-4-phenyl-3-buten-2-one; 4-Fluorobenzylideneacetone; (E)-4-Fluorobenzylideneacetone; 4'-Fluoro-4-phenyl-3-buten-2-one; 3-Buten-2-one, 1-fluoro-4-phenyl-; (E)-1-Fluoro-4-(2-oxoprop-1-en-1-yl)benzene; p-Fluorobenzylideneacetone; 4-Fluorochalcone
EINECS	Contact for details

Quality Control

Our 3-Buten-2-One, 1-Fluoro-4-Phenyl- is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.