Description

2-Butanone,1,1-Difluoro-4-Hydroxy-4-Phenyl-(9Ci) is a specialized fluorinated ketone derivative, identified by CAS number 719279-38-6. This compound is a valuable synthetic intermediate, prized for its unique molecular scaffold that incorporates both fluorine atoms and a hydroxyl group on a phenyl-substituted butanone backbone. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing complex molecules. Its structure makes it a key precursor in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental stability.
• Advanced Material Synthesis: Serves as a monomer or precursor for creating specialty polymers, liquid crystals, or organic electronic materials with tailored properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex organic molecules, leveraging the reactivity of the ketone, hydroxyl, and fluorine functional groups.
• Fluorine Chemistry Studies: A model compound for investigating the effects of fluorine substitution on chemical reactivity and physical properties in organic systems.

Basic Information

Item	Detail
Product Name	2-Butanone,1,1-Difluoro-4-Hydroxy-4-Phenyl-(9Ci)
CAS No.	719279-38-6
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	1,1-Difluoro-4-hydroxy-4-phenylbutan-2-one; 4-Hydroxy-4-phenyl-1,1-difluorobutan-2-one; 4-Phenyl-4-hydroxy-1,1-difluoro-2-butanone; α,α-Difluoro-γ-hydroxy-γ-phenylacetone; γ-Hydroxy-γ-phenyl-α,α-difluoroacetone; (9CI) Index Name; Fluorinated phenyl hydroxy ketone
EINECS	Contact for details

Quality Control

Our 2-Butanone,1,1-Difluoro-4-Hydroxy-4-Phenyl-(9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from NMR (1H, 19F, 13C), HPLC, and GC analysis. Our quality commitment ensures the material meets the exacting standards required for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure (1H, 19F, 13C)
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.