Description

1-Pyrrolidinecarboxylicacid,2-(Aminocarbonyl)-,(2S)-(9Ci) is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in protease inhibitor and peptidomimetic chemistry.
• Asymmetric Synthesis: Used as a building block in catalytic and stoichiometric asymmetric reactions to introduce the (S)-configured proline-like scaffold.
• Peptide Chemistry: Serves as a constrained, unnatural amino acid analog for modifying peptide backbones to enhance stability, bioavailability, or biological activity.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, or plant growth regulators with specific stereochemical requirements.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in metal-catalyzed transformations or organocatalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	1-Pyrrolidinecarboxylicacid,2-(Aminocarbonyl)-,(2S)-(9Ci)
CAS No.	717094-71-8
Molecular Formula	C6H10N2O3
Molecular Weight	158.16 g/mol
Synonyms	(2S)-2-Carbamoylpyrrolidine-1-carboxylic acid; L-Proline, 2-carbamoyl- (9CI); (S)-2-Carbamoylpyrrolidine-1-carboxylic Acid; 2-Carbamoyl-L-proline; (S)-1-Carboxy-2-carbamoylpyrrolidine; (S)-2-Carbamoylpyrrolidine-1-carboxylic Acid; 717094-71-8; (2S)-2-(Aminocarbonyl)-1-pyrrolidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxylicacid,2-(Aminocarbonyl)-,(2S)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, meeting the stringent requirements for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.