Description

1-Naphthonitrile,4-Dimethylamino-5,6,7,8-Tetrahydro- is a specialized tetrahydroquinoline derivative that serves as a high-value intermediate in advanced organic synthesis. Its unique structure, featuring both a nitrile and a dimethylamino group on a partially saturated naphthalene core, makes it a critical building block for constructing complex molecules with specific electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is utilized in the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its fused ring system and amine functionality.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the tetrahydroquinoline scaffold can contribute to biological activity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a starting material for electron-transporting or host materials in OLED devices, leveraging its aromatic and amine character.
• Ligand and Catalyst Development: Serves as a backbone for creating novel chiral or bidentate ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Research: Intermediate for synthesizing advanced colorants and fluorescent markers with tailored photophysical properties.
• Academic and R&D Laboratories: Employed in methodological studies and the exploration of new chemical reactions, such as cyano group transformations.

Basic Information

Product Name	1-Naphthonitrile,4-Dimethylamino-5,6,7,8-Tetrahydro-
CAS No.	713131-90-9
Molecular Formula	C₁₃H₁₆N₂
Molecular Weight	200.28 g/mol
Synonyms	4-(Dimethylamino)-5,6,7,8-tetrahydro-1-naphthonitrile; 4-(Dimethylamino)-5,6,7,8-tetrahydro-1-naphthalenecarbonitrile; 5,6,7,8-Tetrahydro-4-(dimethylamino)-1-naphthonitrile; 1-Cyano-4-(dimethylamino)-5,6,7,8-tetrahydronaphthalene; N,N-Dimethyl-5,6,7,8-tetrahydro-1-naphthylamine-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 1-Naphthonitrile,4-Dimethylamino-5,6,7,8-Tetrahydro- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and Karl Fischer titration for moisture content. Certificates of Analysis (COA) detailing all specifications and results are provided with every shipment. We support custom synthesis and can tailor purity grades, typically from 95% to 98%+, to meet specific research or GMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere (e.g., nitrogen or argon) to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.