Description

(+)-N,n-Bis[(1R)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine, (11Br) is a sophisticated chiral phosphoramidite ligand, a critical class of organocatalysts and auxiliaries in asymmetric synthesis. Its value lies in enabling highly enantioselective transformations, which are essential for producing single-enantiomer pharmaceuticals and fine chemicals. This compound is primarily needed by research institutions and industrial R&D departments focused on developing novel catalytic processes, particularly in the pharmaceutical and advanced materials sectors.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation, hydroformylation, and cross-coupling.
• As an organocatalyst for enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions.
• In the research and development of novel synthetic methodologies for complex natural products and active pharmaceutical ingredients (APIs).
• For the preparation of stereochemically defined intermediates in medicinal chemistry and process chemistry.
• As a key component in catalyst screening kits for high-throughput experimentation (HTE) in drug discovery.
• In academic research for studying structure-activity relationships (SAR) in asymmetric catalysis.

Basic Information

Item	Details
Product Name	(+)-N,n-Bis[(1R)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine, (11Br)
CAS No.	712352-08-4
Molecular Formula	C39H31BrNO2P
Molecular Weight	656.55 g/mol
Synonyms	(11bR)-4-[(R)-1-Phenylethylamino]-N-[(R)-1-phenylethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine 11b-oxide; (R,R)-BINAPO; (R,R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl N-oxide derivative; Chiral phosphoramidite ligand; Asymmetric synthesis ligand; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (+)-N,n-Bis[(1R)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine, (11Br) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR spectroscopy, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding catalytic applications. Certificates of Analysis (COA) with full characterization data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and catalytic activity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.