Description

1-(3'-Trifluoromethyl[1,1'-Biphenyl]-4-Yl)-Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its biphenyl core and trifluoromethyl substituent. This compound is critical for research and development in medicinal chemistry, where its unique structure enables the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutics.
• Organic Synthesis: Serves as a versatile precursor for constructing more complex molecules via cross-coupling and functional group transformations.
• Agrochemical Development: Potential intermediate in the research and synthesis of advanced crop protection agents.
• Material Science: Investigated as a monomer or additive for specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	1-(3'-Trifluoromethyl[1,1'-Biphenyl]-4-Yl)-Ethanone
CAS No.	709667-96-9
Molecular Formula	C15H11F3O
Molecular Weight	264.24 g/mol
Synonyms	4'-Acetyl-3'-(trifluoromethyl)biphenyl; 1-[4-(3-Trifluoromethylphenyl)phenyl]ethanone; 3'-Trifluoromethyl-4-acetylbiphenyl; 4-Acetyl-3'-trifluoromethylbiphenyl; 1-(4'-Acetylphenyl)-3-(trifluoromethyl)benzene; 4-(3-Trifluoromethylphenyl)acetophenone; Biphenyl, 4'-acetyl-3'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 1-(3'-Trifluoromethyl[1,1'-Biphenyl]-4-Yl)-Ethanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.