Description

Boc-(S)- -Allyl-Pro-Oh CAS NO 706806-59-9 is a protected amino acid derivative, specifically a Boc-protected form of (S)-allyl-proline. This compound is a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and fine chemical manufacturers engaged in the development of novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate the unique proline derivative with an allyl-protected side chain.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of protease inhibitors due to the proline scaffold.
• Bioconjugation & Chemical Biology: The allyl group provides a handle for further chemical modification via click chemistry or other coupling reactions for probe and linker development.
• Academic & Industrial Research: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.
• Custom Synthesis: A starting material for the custom synthesis of specialized amino acids and complex organic molecules for contract research organizations (CROs).

Basic Information

Product Name	Boc-(S)- -Allyl-Pro-Oh
CAS No.	706806-59-9
Molecular Formula	C13H21NO4
Molecular Weight	255.31 g/mol
Synonyms	(S)-1-((tert-Butoxycarbonyl)-2-(2-propenyl)pyrrolidine-2-carboxylic acid; Boc-L-Allylproline; Boc-(S)-Allylproline; tert-Butyl (2S)-2-(2-propenyl)-1,2-pyrrolidinedicarboxylate; (S)-2-Allyl-1-Boc-pyrrolidine-2-carboxylic acid; N-Boc-L-allylproline; (S)-1-(tert-Butoxycarbonyl)-2-(2-propenyl)pyrrolidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our Boc-(S)- -Allyl-Pro-Oh is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.