Description

2H-1-Benzopyran-2-One, 8-Fluoro-7-Hydroxy- is a fluorinated coumarin derivative, a high-purity synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to incorporate its unique fluorinated benzopyranone scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new-generation fluorinated pesticides and herbicides, leveraging the bioactivity of the coumarin core.
• Fluorescent Probe Synthesis: Serves as a starting material for creating specialized fluorophores and molecular sensors used in biochemical assays and diagnostics.
• Organic Light-Emitting Diode (OLED) Materials: A potential building block for electron-transport or emissive layer materials in advanced display technologies.
• Academic & Contract Research: Employed in medicinal chemistry and synthetic methodology research for structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Used to produce more complex fluorinated heterocyclic compounds for various specialty chemical applications.

Basic Information

Item	Detail
Product Name	2H-1-Benzopyran-2-One, 8-Fluoro-7-Hydroxy-
CAS No.	705944-49-6
Molecular Formula	C9H5FO3
Molecular Weight	180.13 g/mol
Synonyms	8-Fluoro-7-hydroxycoumarin; 7-Hydroxy-8-fluorocoumarin; 8-Fluoro-7-hydroxy-2H-chromen-2-one; 8-Fluoro-7-hydroxy-2H-1-benzopyran-2-one; 8-Fluoroumbelliferone; Fluorohydroxycoumarin
EINECS	Contact for details

Quality Control

Our 2H-1-Benzopyran-2-One, 8-Fluoro-7-Hydroxy- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and quality assurance for your projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.