Description

3-[3-(Trifluoromethoxy)Phenyl]-2-Propenoic Acid Methyl Ester is a high-purity fluorinated organic intermediate with significant utility in advanced chemical synthesis. This compound, identified by CAS number 705250-76-6, is valued for its trifluoromethoxy-substituted aromatic structure, which imparts unique electronic and steric properties to target molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in areas targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving performance characteristics.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, and specific optical properties.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in medicinal chemistry, material science, and fluorine chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, complex fluorinated intermediates.

Basic Information

Product Name	3-[3-(Trifluoromethoxy)Phenyl]-2-Propenoic Acid Methyl Ester
CAS No.	705250-76-6
Molecular Formula	C11H9F3O3
Molecular Weight	246.18 g/mol
Synonyms	Methyl 3-[3-(Trifluoromethoxy)phenyl]acrylate; Methyl (E)-3-[3-(Trifluoromethoxy)phenyl]propenoate; 3-(3-Trifluoromethoxyphenyl)acrylic Acid Methyl Ester; (E)-Methyl 3-(3-(Trifluoromethoxy)phenyl)acrylate; 705250-76-6; 3-(3-Trifluoromethoxy-phenyl)-acrylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of 3-[3-(Trifluoromethoxy)Phenyl]-2-Propenoic Acid Methyl Ester adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our facilities operate under ISO 9001 quality standards, and we support regulatory documentation for REACH and other global chemical inventories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.