Description

Ba-D-Ribofuranoside, Ethyl 5-Deoxy-5-Fluoro-2,3-o-(1-Methylethylidene)- (9Ci) is a high-purity, fluorinated ribofuranoside derivative, a crucial synthetic intermediate in modern pharmaceutical research and development. Its core value lies in its role as a sophisticated building block for the synthesis of novel nucleoside analogs, which are pivotal in the creation of antiviral and anticancer therapeutics. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated nucleoside analogs with potential antiviral (e.g., anti-HIV, anti-hepatitis) and anticancer activity.
• Antiviral Drug Research: Used in the research and development of novel therapeutic agents targeting viral polymerases and reverse transcriptases.
• Oncology Research: Serves as a precursor in the development of chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Probe Development: Utilized to create labeled or modified nucleosides for studying enzymatic mechanisms and metabolic pathways.
• Process Chemistry & Scale-Up: Employed in the optimization and pilot-scale production of active pharmaceutical ingredients (APIs) requiring fluorinated sugar moieties.
• Academic & Institutional Research: A valuable reagent for universities and research institutes exploring carbohydrate chemistry and medicinal chemistry.

Basic Information

Item	Detail
Product Name	Ba-D-Ribofuranoside, Ethyl 5-Deoxy-5-Fluoro-2,3-o-(1-Methylethylidene)- (9Ci)
CAS No.	704916-07-4
Molecular Formula	C12H19FO5
Molecular Weight	262.27 g/mol
Synonyms	Ethyl 5-deoxy-5-fluoro-2,3-O-isopropylidene-β-D-ribofuranoside; 5-Deoxy-5-fluoro-2,3-O-isopropylidene-β-D-ribofuranoside ethyl ether; 1-Ethoxy-5-fluoro-2,3-O-isopropylidene-β-D-ribofuranose; Ethyl 5-fluoro-5-deoxy-2,3-O-(1-methylethylidene)-β-D-ribofuranoside; β-D-Ribofuranoside, ethyl 5-deoxy-5-fluoro-2,3-O-(1-methylethylidene)-; 704916-07-4; 5-Fluoro-5-deoxy-2,3-O-isopropylidene ethyl β-D-ribofuranoside
EINECS	Contact for details

Quality Control

Our Ba-D-Ribofuranoside, Ethyl 5-Deoxy-5-Fluoro-2,3-o-(1-Methylethylidene)- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.