Description

tert-Butyl [(1S)-1-(3-Bromo-4-Methoxyphenyl)Ethyl]Carbamate is a high-purity chiral intermediate of significant importance in modern synthetic chemistry. This compound is valued for its role as a key building block in the synthesis of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research institutions and manufacturers engaged in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where stereochemical purity is a critical parameter for efficacy and regulatory approval.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the multi-step synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• API Development: Serves as a key precursor in constructing the core scaffold of target molecules during the Active Pharmaceutical Ingredient (API) development process.
• Asymmetric Synthesis: Utilized in stereoselective reactions to introduce a specific chiral center, enabling the production of enantiomerically pure compounds.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular architectures.
• Process Chemistry: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales for new chemical entities.

Basic Information

Product Name	tert-Butyl [(1S)-1-(3-Bromo-4-Methoxyphenyl)Ethyl]Carbamate
CAS No.	701939-09-5
Molecular Formula	C14H20BrNO3
Molecular Weight	330.22 g/mol
Synonyms	(1S)-1-(3-Bromo-4-methoxyphenyl)ethyl carbamic acid tert-butyl ester; tert-Butyl N-[(1S)-1-(3-bromo-4-methoxyphenyl)ethyl]carbamate; Boc-L-3-Bromo-4-methoxy-α-methylbenzylamine; (S)-tert-Butyl (1-(3-bromo-4-methoxyphenyl)ethyl)carbamate; N-Boc-1-(3-Bromo-4-methoxyphenyl)ethanamine (S-enantiomer); (S)-1-(3-Bromo-4-methoxyphenyl)ethylcarbamic acid tert-butyl ester; Boc-(S)-3-Bromo-4-methoxy-α-methylbenzylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl [(1S)-1-(3-Bromo-4-Methoxyphenyl)Ethyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.