Description

2-Bromo-4-Ethenyl-1-Fluorobenzene is a halogenated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of bromine and fluorine substituents, which allows for selective functionalization and tuning of electronic properties in target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Stille couplings to form biaryl structures.
• Fluorine Chemistry Exploration: Acts as a valuable model compound for studying the influence of fluorine on aromatic systems in medicinal and materials chemistry.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical companies offering bespoke synthesis services for client-specific molecular targets.

Basic Information

Product Name	2-Bromo-4-Ethenyl-1-Fluorobenzene
CAS No.	701914-09-2
Molecular Formula	C8H6BrF
Molecular Weight	201.04 g/mol
Synonyms	1-Bromo-2-fluoro-4-vinylbenzene; 2-Fluoro-4-vinylbromobenzene; 4-Ethenyl-2-bromofluorobenzene; 2-Bromo-4-vinylfluorobenzene; 4-Vinyl-2-bromo-1-fluorobenzene; Benzene, 2-bromo-4-ethenyl-1-fluoro-; (2-Bromo-4-fluorophenyl)ethylene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Ethenyl-1-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.