Description

2-Pyrrolidinecarbonitrile,1-Acetyl-,(2S)-(9Ci) is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters as a key building block for the development of novel pharmaceuticals and agrochemicals, enabling the construction of complex, stereochemically defined molecular architectures. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for process development and the synthesis of active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Research: Used in the discovery and development of new, stereoselective pesticides and herbicides where specific chirality is essential for biological activity.
• Asymmetric Catalysis: Serves as a precursor or ligand component in the development of chiral catalysts for enantioselective synthesis.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.
• Academic & Industrial R&D: A valuable reagent for methodological research in organic chemistry, exploring new synthetic routes and reaction mechanisms.

Basic Information

Product Name	2-Pyrrolidinecarbonitrile,1-Acetyl-,(2S)-(9Ci)
CAS No.	700376-84-7
Molecular Formula	C7H10N2O
Molecular Weight	138.17 g/mol
Synonyms	(2S)-1-Acetyl-2-pyrrolidinecarbonitrile; (S)-1-Acetyl-2-cyanopyrrolidine; 1-Acetyl-2-cyano-(S)-pyrrolidine; (S)-1-Acetylpyrrolidine-2-carbonitrile; 2-Cyano-1-acetyl-(S)-pyrrolidine; (S)-N-Acetyl-2-cyanopyrrolidine; Pyrrolidine-2-carbonitrile, 1-acetyl-, (2S)-; 700376-84-7
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinecarbonitrile,1-Acetyl-,(2S)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.