Description

Dynorphin A (1-10) Amide is a bioactive peptide fragment derived from the endogenous opioid peptide Dynorphin A. This compound is of significant interest in neuroscience and pharmaceutical research due to its role as a potent and selective κ-opioid receptor (KOR) agonist. It serves as a critical research tool for studying pain pathways, addiction mechanisms, and neuropsychiatric disorders. Researchers and developers in neuropharmacology, peptide chemistry, and drug discovery require this high-purity reference standard for their investigative and development work.

Application

• Neuroscience Research: As a selective κ-opioid receptor (KOR) agonist for studying receptor function, signal transduction, and behavioral effects in animal models.
• Pain Pathway Analysis: Investigation of endogenous pain modulation systems and the development of novel analgesic targets.
• Addiction and Reward Studies: Research into the dysphoric effects of KOR activation and its implications for substance abuse and dependence.
• Neuropsychiatric Disorder Research: Exploration of KOR's role in stress, depression, and anxiety for potential therapeutic applications.
• Biochemical Assay Development: Use as a reference standard or control in receptor binding assays, functional cell-based assays, and ELISA development.
• Peptide Chemistry & Analog Development: Serving as a lead structure or intermediate for the synthesis of novel peptide analogs with modified pharmacological profiles.
• Academic & Institutional Research: A key reagent for university and government laboratory studies focused on opioid neurobiology.

Basic Information

Item	Details
Product Name	Dynorphin A (1-10) Amide
CAS No.	79985-49-2
Molecular Formula	C58H85N17O12
Molecular Weight	1180.4 g/mol
Synonyms	Dynorphin A (1-10) amide; Dynorphin A 1-10 amide; [Des-Leu]-Dynorphin A (1-11) amide; Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-NH2; YGGFLRRIRP-NH2; Dynorphin A (1-10)-NH2; Dynorphin A 1-10-NH2
EINECS	Contact for details

Quality Control

Every batch of Dynorphin A (1-10) Amide is manufactured and analyzed under strict quality management protocols. Our products undergo rigorous purity and identity verification using advanced analytical techniques including HPLC and mass spectrometry to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and other critical parameters, is provided with each shipment to guarantee traceability and batch-to-batch consistency for your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.