Description

Polyketide Synthase CAS NO 79956-01-7 is a critical enzyme complex central to the biosynthesis of polyketides, a vast and structurally diverse class of natural products. This biocatalyst enables the precise, modular assembly of simple acyl-CoA precursors into complex molecular scaffolds with significant biological activity. It is an essential research and production tool for scientists and manufacturers in the pharmaceutical, agrochemical, and biotechnology sectors seeking to develop novel antibiotics, anticancer agents, statins, and other high-value compounds through synthetic biology and metabolic engineering.

Application

• Pharmaceutical Research & Development: Key enzyme for the biosynthesis and engineered production of antibiotic compounds (e.g., erythromycin, tetracycline), anticancer drugs, and immunosuppressants.
• Metabolic Engineering & Synthetic Biology: Used to design and construct novel biosynthetic pathways in microbial hosts for the sustainable production of complex polyketides.
• Enzymology & Biochemical Studies: Serves as a model system for studying modular enzyme architecture, substrate specificity, and catalytic mechanisms in complex biosynthesis.
• Agrochemical Discovery: Involved in producing natural product-derived fungicides, herbicides, and insecticides with novel modes of action.
• Academic Research: Fundamental tool for investigating natural product biosynthesis, enzyme evolution, and pathway regulation.
• Biocatalyst Development: Explored for the in vitro synthesis of specialty chemicals and chiral building blocks through cell-free systems.

Basic Information

Item	Detail
Product Name	Polyketide Synthase
CAS No.	79956-01-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PKS; 6-Methylsalicylic acid synthase; 6-MSA synthase; 6-Methylsalicylate synthase; Polyketide synthetase; (6-Methylsalicylate) synthase; 2,4-Dihydroxy-6-methylbenzoate synthase
EINECS	Contact for details

Quality Control

Our Polyketide Synthase is produced and handled under stringent quality management protocols to ensure batch-to-batch consistency and optimal enzymatic activity. Each lot is subjected to rigorous analytical testing, including activity assays, purity assessment via electrophoresis (SDS-PAGE), and protein concentration determination. A comprehensive Certificate of Analysis (COA) detailing specific activity, purity, buffer composition, and storage conditions is provided with every shipment to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent moisture uptake and loss of activity. Handle according to standard laboratory safety practices for biological materials.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms (Catalyzes formation of 6-methylsalicylic acid)
Protein Content (Bradford)	≥ 90% of total protein
Specific Activity	Contact for details
Purity (SDS-PAGE)	≥ 90%
Buffer Composition	Tris-HCl, Glycerol, DTT (typical)
pH	7.0 - 8.0
Endotoxin Level	< 1.0 EU/µg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.