Description

Epi Lovastatin CAS NO 79952-44-6 is a key pharmaceutical intermediate and stereoisomer of the cholesterol-lowering agent Lovastatin. This compound is of significant interest for research and development in the synthesis of novel statin derivatives and for studying structure-activity relationships. It serves as a critical building block for pharmaceutical manufacturers and advanced research institutions focused on cardiovascular therapeutics and metabolic disease research.

Application

• Pharmaceutical Intermediate: Primary use in the research and synthesis of novel HMG-CoA reductase inhibitors (statins) and their analogs.
• Reference Standard: Serves as a high-purity chemical reference standard (CRS) for analytical method development and quality control in pharmaceutical labs.
• Metabolic Research: Used in biochemical and pharmacological studies to investigate cholesterol biosynthesis pathways and enzyme inhibition mechanisms.
• Process Chemistry: Employed in the development and optimization of stereoselective synthesis routes for complex pharmaceutical molecules.
• Academic Research: A valuable tool for universities and research institutes studying organic synthesis, medicinal chemistry, and drug discovery.

Basic Information

Product Name	Epi Lovastatin
CAS No.	79952-44-6
Molecular Formula	C24H36O5
Molecular Weight	404.54 g/mol
Synonyms	(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl (2S)-2-methylbutanoate; 6α-Methylcompactin; Epilovastatin; Lovastatin EP Impurity C; Monacolin J; 3α-Hydroxylovastatin
EINECS	Contact for details

Quality Control

Our Epi Lovastatin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and pharmaceutical use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.