Description

2,5-Diiodobenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its unique structure, featuring two iodine atoms in specific positions on the benzonitrile core, makes it a critical intermediate for constructing complex molecules in pharmaceutical and materials science research. This high-purity compound is essential for chemists and manufacturers engaged in cross-coupling reactions, ligand synthesis, and the development of active pharmaceutical ingredients (APIs) and liquid crystal materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring halogenated aromatic scaffolds for activity.
• Cross-Coupling Reactions: Serves as a valuable substrate in palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings to form biaryl and other carbon-carbon bonds.
• Ligand and Catalyst Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Employed as a building block for developing novel herbicides, fungicides, and pesticides.
• Material Science: A monomer or precursor in the synthesis of polymers and advanced materials, including liquid crystals and organic semiconductors.
• Chemical Synthesis: Utilized in various organic transformations, including nucleophilic aromatic substitution and cyano group modifications.

Basic Information

Product Name	2,5-Diiodobenzonitrile
CAS No.	79887-24-4
Molecular Formula	C7H3I2N
Molecular Weight	354.92 g/mol
Synonyms	2,5-Diiodobenzonitrile; Benzonitrile, 2,5-diiodo-; 2,5-Diiodophenyl cyanide; 2,5-Bis(iodo)benzonitrile; 79887-24-4; AI3-26036; SCHEMBL11806279; ZINC3867894
EINECS	Contact for details

Quality Control

Our 2,5-Diiodobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment ensures material consistency and reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.