Description

2,5-Furandione, 3,3-Difluorodihydro- is a specialized fluorinated succinic anhydride derivative, a high-value building block in advanced organic synthesis. Its unique structure, featuring a reactive anhydride moiety flanked by fluorine atoms, makes it a critical intermediate for introducing fluorinated motifs into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors seeking to develop novel compounds with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atoms improve biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or cross-linking agent for creating fluorinated polymers with unique surface properties, chemical resistance, and thermal stability.
• Ligand and Catalyst Development: Employed in the design of novel fluorinated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A versatile reagent for academic and industrial research exploring new fluorination methodologies and the synthesis of complex fluoroorganic compounds.
• Fine Chemical Production: Intermediate in the manufacture of fluorinated dyes, flavors, and fragrances.

Basic Information

Product Name	2,5-Furandione, 3,3-Difluorodihydro-
CAS No.	79802-73-6
Molecular Formula	C4H2F2O3
Molecular Weight	136.06 g/mol
Synonyms	3,3-Difluorodihydro-2,5-furandione; 3,3-Difluorosuccinic Anhydride; 2,5-Dihydro-3,3-difluorofuran-2,5-dione; 3,3-Difluorotetrahydrofuran-2,5-dione; Difluorosuccinic Anhydride; 3,3-Difluorooxolane-2,5-dione
EINECS	Contact for details

Quality Control

Our 2,5-Furandione, 3,3-Difluorodihydro- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis of the anhydride functionality. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.