Description

3-Iodo-n-[(Benzyloxy)Carbonyl]-L-Tyrosine is a protected, iodinated derivative of the essential amino acid L-tyrosine, widely used as a key synthetic intermediate in advanced organic and peptide chemistry. This compound is crucial for researchers and manufacturers requiring site-specific modification of tyrosine residues, enabling the development of novel bioactive molecules and radiopharmaceutical precursors. It is primarily utilized by pharmaceutical R&D teams, peptide synthesis specialists, and fine chemical producers engaged in creating targeted therapeutics and diagnostic agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel peptide-based drugs and targeted therapeutics.
• Radiopharmaceutical Precursor: Used in the development of iodine-123 or iodine-131 labeled compounds for diagnostic imaging and targeted radiotherapy.
• Peptide Chemistry Research: Enables site-specific iodination and functionalization of tyrosine residues within peptide chains for structure-activity relationship (SAR) studies.
• Bioconjugation: Serves as a versatile linker or handle for attaching peptides to other molecules, surfaces, or nanoparticles.
• Proteomics & Biochemical Tool Development: Used to create affinity probes, enzyme inhibitors, or activity-based protein profiling (ABPP) reagents.
• Fine Chemical Synthesis: An advanced intermediate in multi-step organic syntheses for complex natural product analogs and specialty chemicals.

Basic Information

Product Name	3-Iodo-n-[(Benzyloxy)Carbonyl]-L-Tyrosine
CAS No.	79677-62-6
Molecular Formula	C17H16INO5
Molecular Weight	465.22 g/mol
Synonyms	N-Cbz-3-Iodo-L-tyrosine; (S)-2-(((Benzyloxy)carbonyl)amino)-3-(4-hydroxy-3-iodophenyl)propanoic acid; Z-3-Iodo-L-Tyrosine-OH; Cbz-3-Iodo-L-Tyrosine; 3-Iodo-L-tyrosine, N-[(benzyloxy)carbonyl]-; 3-Iodo-N-carbobenzoxy-L-tyrosine; Nα-Carbobenzoxy-3-iodo-L-tyrosine; 79677-62-6
EINECS	Contact for details

Quality Control

Our 3-Iodo-n-[(Benzyloxy)Carbonyl]-L-Tyrosine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric integrity, and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥97.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.