Description

Cholecystokinin Octapeptide, Des-Nh2-Tyr is a synthetic bioactive peptide fragment derived from the gastrointestinal hormone cholecystokinin (CCK). This compound is of significant value for research and development due to its specific receptor binding activity, making it a critical tool for studying digestive processes, satiety signaling, and neurological functions. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on metabolic and central nervous system disorders.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating CCK receptor subtypes (CCKA and CCKB) and their roles in physiology and disease.
• Drug Discovery & Development: Serves as a key intermediate or lead compound in the development of novel therapeutics targeting appetite regulation, pain management, and anxiety.
• Biochemical Assays: Employed in receptor binding assays, functional cell-based tests, and enzyme-linked immunosorbent assays (ELISAs) to validate experimental systems.
• Neuroscience Studies: Applied in research exploring the gut-brain axis, the role of CCK in memory, learning, and panic responses.
• Academic & Clinical Research: Provides a high-purity material for in vitro and in vivo studies on gastrointestinal motility, pancreatic secretion, and satiety mechanisms.

Basic Information

Product Name	Cholecystokinin Octapeptide, Des-Nh2-Tyr
CAS No.	79672-08-5
Molecular Formula	C48H62N10O14S2
Molecular Weight	1043.2 g/mol
Synonyms	CCK-8 (desulfated); Desulfated Cholecystokinin Octapeptide; CCK-8, Desulfated; Sincalide, Desulfated; SQ 19,844; Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 (Desulfated); Cholecystokinin (26-33), desulfated; CCK (26-33), desulfated
EINECS	Contact for details

Quality Control

Our Cholecystokinin Octapeptide, Des-Nh2-Tyr is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide Certificates of Analysis (COA) with detailed specifications for trace impurities, residual solvents, and peptide content to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Peptide Content (AAA)	≥ 80.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.