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3-Dansylamidomethyl-7-Beta(Thienyl-2')-Acetamidoceph-3-Em-4-Oate CAS NO 79645-00-4


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CAS No.:79645-00-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Dansylamidomethyl-7-Beta(Thienyl-2')-Acetamidoceph-3-Em-4-Oate is a specialized, high-purity chemical intermediate primarily used in advanced pharmaceutical research and development. This compound is critical for the synthesis and structural modification of cephalosporin antibiotics, offering a unique dansyl-labeled derivative for analytical and synthetic applications. It is an essential building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on developing next-generation antimicrobial agents.

Application

  • Pharmaceutical Intermediate: Key synthetic precursor in the research and production of novel cephalosporin-class antibiotics.
  • Fluorescent Labeling & Probes: Utilized in biochemical research as a dansyl-tagged derivative for fluorescence-based assays, receptor binding studies, and enzyme activity monitoring.
  • Analytical Reference Standard: Serves as a high-purity certified reference material (CRM) for quality control, method validation, and regulatory compliance in pharmaceutical analysis.
  • Structure-Activity Relationship (SAR) Studies: Employed in medicinal chemistry to investigate the impact of structural modifications on the biological activity and pharmacokinetic properties of β-lactam antibiotics.
  • Academic & Industrial Research: Used in university and corporate R&D labs for exploring new synthetic pathways and mechanisms of action for antibacterial agents.

Basic Information

Product Name 3-Dansylamidomethyl-7-Beta(Thienyl-2')-Acetamidoceph-3-Em-4-Oate
CAS No. 79645-00-4
Molecular Formula C31H30N4O7S2
Molecular Weight 634.72 g/mol
Synonyms 7β-[(2-Thienylacetyl)amino]-3-[[(5-dimethylamino-1-naphthyl)sulfonyl]aminomethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Dansyl Cephalosporin Derivative; 3-(Dansylaminomethyl)-7-(2-thienylacetamido)ceph-3-em-4-carboxylic Acid; Cephalosporin Dansylamide; 79645-00-4; 7-ACA Dansyl Derivative
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Quality Control

Our 3-Dansylamidomethyl-7-Beta(Thienyl-2')-Acetamidoceph-3-Em-4-Oate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance Yellow to light brown powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH Q3C guidelines
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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