Description

Cerebratulus Lacteus Toxin B-Ii is a potent polypeptide neurotoxin isolated from the marine ribbon worm, *Cerebratulus lacteus*. This compound is of significant interest for its specific and high-affinity interaction with voltage-gated sodium channels, making it a valuable tool for neurological and pharmacological research. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in ion channel studies, neurophysiology, and the development of novel therapeutic agents.

Application

• Neuroscience Research: As a specific probe for studying the structure, function, and modulation of voltage-gated sodium channels (NaV channels) in neuronal cells.
• Pharmacological Screening: Used in high-throughput assays to identify and characterize new compounds that modulate sodium channel activity for potential drug discovery.
• Toxin-Antitoxin Studies: Serves as a reference standard in the development and validation of detection methods or neutralizing antibodies.
• Cellular Physiology: Employed to investigate action potential generation, nerve conduction, and synaptic transmission in experimental models.
• Biochemical Reagent: Used in protein-protein interaction studies to map binding sites on sodium channel subunits.
• Academic & Industrial R&D: Essential for basic research in neurobiology and applied research in pain management, cardiology, and neurology fields.

Basic Information

Product Name	Cerebratulus Lacteus Toxin B-Ii
CAS No.	79586-20-2
Molecular Formula	C184H281N51O55S6
Molecular Weight	~4200 Da (Contact for exact mass)
Synonyms	Cerebratulus Toxin BII; CLTX B-II; Cerebratulus lacteus neurotoxin BII; Sodium channel neurotoxin BII; B-II Toxin; Polypeptide neurotoxin BII; NaV channel toxin BII; Ribbon worm toxin BII
EINECS	Contact for details

Quality Control

Our Cerebratulus Lacteus Toxin B-Ii is produced and handled under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot is subjected to rigorous analytical testing, including HPLC for purity assessment and mass spectrometry for identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, bioactivity (where applicable), and analytical methods is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. Aliquot into single-use vials to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Protein Content (UV)	≥ 90%
Biological Activity	Contact for details
Endotoxin Level	< 1.0 EU/µg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.