Description

Methanopterin CAS NO 79484-89-2 is a specialized pterin derivative and a key coenzyme involved in one-carbon transfer reactions in methanogenic and other archaea and bacteria. Its primary commercial value lies in its role as a critical biochemical reagent and research standard for studying C1 metabolism, methanogenesis, and enzyme mechanisms. This high-purity compound is essential for researchers and developers in academic biochemistry, pharmaceutical R&D for antimicrobial discovery, and industrial biotechnology sectors focusing on metabolic engineering and novel biosynthetic pathways.

Application

• Biochemical Research: Essential cofactor in studies of methanogenesis and one-carbon metabolism in archaea.
• Enzyme Kinetics & Mechanism Studies: Used as a substrate or standard for characterizing enzymes like tetrahydromethanopterin-dependent methyltransferases.
• Pharmaceutical R&D: Investigated in antimicrobial discovery targeting unique methanogen pathways.
• Metabolic Pathway Analysis: A critical reagent for tracing and understanding C1 unit transfer in synthetic biology.
• Diagnostic Kit Development: Potential use as a component in enzymatic assays for research purposes.
• Reference Standard: Serves as a high-purity calibrant for analytical methods (HPLC, MS) in research laboratories.

Basic Information

Product Name	Methanopterin
CAS No.	79484-89-2
Molecular Formula	C30H38N10O13P2
Molecular Weight	808.64 g/mol
Synonyms	5,6,7,8-Tetrahydromethanopterin; H4MPT; Tetrahydromethanopterin; Coenzyme Methanopterin; 5,6,7,8-Tetrahydrosarcinapterin; Sarcinapterin; 1,5,6,7,8-Pentahydro-2-methyl-4,7-dioxo-8-D-ribofuranosylpteridine-6-carboxamide
EINECS	Contact for details

Quality Control

Our Methanopterin is manufactured under controlled conditions to ensure high batch-to-batch consistency and purity suitable for advanced research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment, NMR for structural confirmation, and mass spectrometry for identity verification. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95%
Water Content (Karl Fischer)	≤ 3.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.