Description

Ferritin is a ubiquitous and essential iron-storage protein complex found across biological systems. Its primary function is to sequester iron in a non-toxic, bioavailable form, playing a critical role in cellular iron homeostasis and detoxification. This product is vital for research and development in the life sciences, biotechnology, and pharmaceutical industries, where it serves as a key reagent for studying iron metabolism, developing diagnostic assays, and exploring novel therapeutic platforms.

Application

• Biomedical Research: Fundamental studies on iron metabolism, oxidative stress, and related metabolic pathways.
• Diagnostic Development: Used as a standard or component in immunoassays for measuring serum ferritin levels, a key clinical marker for iron deficiency and overload disorders.
• Nanotechnology & Drug Delivery: Exploiting its hollow protein cage structure for the encapsulation and targeted delivery of therapeutic agents, imaging probes, or catalysts.
• Biomaterial Synthesis: Template for the synthesis of uniform inorganic nanoparticles due to its precise interior cavity.
• Nutritional Science: Research into iron bioavailability and the development of fortified food products.
• Therapeutic Protein Research: Investigation into ferritin's role in inflammation, immunity, and its potential as a vaccine platform or therapeutic target.

Basic Information

Product Name	Ferritin
CAS No.	79468-83-0
Molecular Formula	Variable (Protein Complex)
Molecular Weight	~440-480 kDa (Apoferritin Shell)
Synonyms	Apoferritin; Iron Storage Protein; Ferritin Heavy Chain; Ferritin Light Chain; FTH1; FTL; Native Ferritin; Recombinant Ferritin; Serum Ferritin; Tissue Ferritin
EINECS	Contact for details

Quality Control

Our Ferritin is produced and handled under stringent quality management protocols. Each lot is subjected to a comprehensive battery of analytical tests to ensure identity, purity, and functional integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as protein concentration, iron content, oligomeric state, and purity assessed by HPLC and electrophoresis. We adhere to relevant guidelines for research-grade biological products.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C. Reconstituted solutions should be aliquoted and stored at -80°C to prevent repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use.

Specification

Item	Specification
Appearance	White or light-colored lyophilized powder
Identification (SDS-PAGE / Immunoassay)	Conforms to standard
Protein Content (UV Absorbance / BCA)	> 95%
Purity (HPLC / SEC)	> 90% (monomeric form)
Iron Content (ICP-MS / Colorimetric Assay)	Variable by grade (Apo or Holo form)
Endotoxin Level (LAL Test)	< 1.0 EU/mg (for cell culture grades)
Solubility	Soluble in aqueous buffers (e.g., PBS, Tris)
Biological Activity	Confirmed by functional assay (e.g., iron loading)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.