Description

7-(5-Carboxypentyl)Guanosine 5'-Diphosphate is a chemically modified nucleotide analog, specifically a guanosine derivative functionalized with a carboxypentyl chain at the 7-position. This modification is critical for its role as a potent and selective inhibitor of certain GTP-binding proteins and enzymes, making it a valuable tool compound in biochemical research. It is primarily utilized by researchers and manufacturers in the life sciences sector for studying signal transduction pathways, enzyme kinetics, and cellular regulation. The compound's high purity and specificity are essential for reliable experimental results in advanced pharmacological and molecular biology applications.

Application

• Biochemical Research: As a high-affinity inhibitor for studying the function and regulation of specific GTPases and nucleotide-binding proteins.
• Enzyme Assay Development: Used in the development of diagnostic and screening assays targeting enzymes that interact with modified GDP/GTP analogs.
• Signal Transduction Studies: A key tool for probing intracellular signaling cascades, particularly those involving small G-proteins.
• Pharmaceutical R&D: Serves as a reference standard or lead compound in drug discovery programs focused on modulating nucleotide-dependent processes.
• Diagnostic Reagent Manufacturing: Potential component in the formulation of specialized diagnostic kits for research use.
• Academic Research: Employed in university and institutional labs for fundamental research in cell biology and biochemistry.

Basic Information

Product Name	7-(5-Carboxypentyl)Guanosine 5'-Diphosphate
CAS No.	79441-38-6
Molecular Formula	C16H24N5O14P2
Molecular Weight	572.33 g/mol
Synonyms	7-(5-Carboxypentyl)-GDP; GDP-7-(5-Carboxypentyl) analog; 7-Pentanoic acid-GDP; Guanosine-5'-diphosphate, 7-(5-carboxypentyl)-; 7-(5-Carboxypentyl)guanosine diphosphate; 7-CPGDP; Modified GDP inhibitor; GTPase inhibitor analog
EINECS	Contact for details

Quality Control

Our 7-(5-Carboxypentyl)Guanosine 5'-Diphosphate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting compliance with internal quality standards for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.