Description

2,2,2-Trifluoroacetic Acid Octadecyl Ester is a high-purity fluorinated ester compound, valued for its unique combination of a long alkyl chain and a trifluoroacetate group. This structure makes it a versatile intermediate and functional additive, particularly useful for modifying surface properties and imparting lipophilicity and chemical resistance. It is essential for manufacturers and researchers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop specialized fluorinated products.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, where the fluorinated ester group can enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Serves as a key building block for creating advanced herbicides, pesticides, and fungicides with improved efficacy and environmental profiles.
• Surface Modification Agent: Acts as a hydrophobic and oleophobic coating precursor for textiles, polymers, and electronic components.
• Lubricant & Grease Additive: Imparts thermal and chemical stability to high-performance lubricants and functional fluids.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter surface energy, reduce friction, and enhance solvent resistance.
• Analytical Chemistry: Employed as a derivatization agent in chromatography (GC, LC) for the analysis of long-chain alcohols and amines.
• Flavor & Fragrance Ingredient: Used in the synthesis of specific ester-based aroma chemicals.
• Research & Development: A valuable reagent in organic synthesis for introducing the trifluoroacetate protecting group or the octadecyl chain.

Basic Information

Product Name	2,2,2-Trifluoroacetic Acid Octadecyl Ester
CAS No.	79392-43-1
Molecular Formula	C₂₀H₃₇F₃O₂
Molecular Weight	366.51 g/mol
Synonyms	Octadecyl Trifluoroacetate; Stearyl Trifluoroacetate; n-Octadecyl 2,2,2-Trifluoroacetate; Trifluoroacetic Acid Stearyl Ester; 1-Octadecanol, Trifluoroacetate; Trifluoroacetic Acid Octadecyl Ester; ODA-TFA; Stearyl Alcohol Trifluoroacetate
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoroacetic Acid Octadecyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay, identity (IR, NMR), and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and sources of ignition. Due to its sensitivity to light and potential reactivity with strong alkalis, ensure the container is kept sealed to exclude moisture and contaminants.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Purity (GC Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.