Description

Cefixime CAS NO 79350-37-1 is a third-generation, broad-spectrum cephalosporin antibiotic belonging to the β-lactam class. It is valued for its potent activity against a wide range of Gram-positive and Gram-negative bacteria, including β-lactamase-producing strains. This makes it a critical active pharmaceutical ingredient (API) for manufacturers in the pharmaceutical industry, particularly for formulating oral dosage forms such as tablets, capsules, and suspensions to treat various bacterial infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of oral antibiotic formulations.
• Tablet & Capsule Production: Direct compression or granulation processes for solid oral dosage forms.
• Oral Suspension/Syrup: Used in pediatric and geriatric formulations requiring liquid administration.
• Generic Drug Manufacturing: Sourcing for cost-effective production of generic cefixime medications.
• Contract Manufacturing (CMO): Supply to contract development and manufacturing organizations (CDMOs) for formulation development.
• Veterinary Pharmaceuticals: Potential application in veterinary medicine for treating bacterial infections in animals.
• Research & Development: Used in pharmaceutical R&D for stability studies, analytical method development, and new formulation research.

Basic Information

Product Name	Cefixime
CAS No.	79350-37-1
Molecular Formula	C16H15N5O7S2
Molecular Weight	453.45 g/mol
Synonyms	(6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(carboxymethoxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefixime Trihydrate; Cefiximum; FK-027; FR-17027; CL-284635; Suprax (brand name); Cephoral
EINECS	Contact for details

Quality Control

Our Cefixime is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure compliance with major pharmacopeial standards such as USP, EP, and BP. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request to ensure full traceability and regulatory compliance for your pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 10.0% (for trihydrate)
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	-75° to -90°
pH (Suspension)	2.5 - 4.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.