Description

Ceftriaxone Impurity CAS NO 79221-95-7 is a high-purity chemical reference standard used for analytical and research purposes. This compound is critical for ensuring the quality, safety, and regulatory compliance of the widely used antibiotic Ceftriaxone. It is primarily required by pharmaceutical manufacturers, quality control laboratories, and research institutions involved in drug development and impurity profiling. The availability of this well-characterized impurity standard is essential for method validation, stability studies, and meeting stringent pharmacopeial requirements.

Application

• Pharmaceutical Reference Standard for analytical method development and validation.
• Quality Control (QC) and Quality Assurance (QA) testing of Ceftriaxone Sodium active pharmaceutical ingredient (API) and finished formulations.
• Stability and forced degradation studies to identify and quantify potential degradants.
• Research and Development (R&D) for impurity synthesis, characterization, and toxicological assessment.
• Calibration of analytical instruments such as High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography-Mass Spectrometry (LC-MS).
• Preparation of certified impurity standards for regulatory documentation and submissions (e.g., to FDA, EMA).
• Academic research in the field of antibiotic chemistry, degradation pathways, and analytical science.

Basic Information

Product Name	Ceftriaxone Impurity
CAS No.	79221-95-7
Molecular Formula	C18H18N8O7S2
Molecular Weight	522.51 g/mol
Synonyms	(6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Ceftriaxone Impurity A; Ceftriaxone Related Compound A; 3-[[(2-Methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)thio]methyl]ceftriaxone; 79221-95-7
EINECS	Contact for details

Quality Control

Our Ceftriaxone Impurity is manufactured under strict quality systems and undergoes rigorous analytical testing to ensure it meets the highest standards for pharmaceutical reference materials. Each batch is characterized and controlled against pharmacopeial standards where applicable. A comprehensive Certificate of Analysis (COA) is provided, detailing purity, identity, and impurity profile as determined by advanced techniques like HPLC and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference spectrum
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual unknown impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.