Description

5-(Carbamoyl)-2,4,6-Triiodoisophthalic Acid is a high-purity, tri-iodinated aromatic compound that serves as a critical intermediate in the synthesis of advanced X-ray contrast media. Its molecular structure, featuring three iodine atoms and a carbamoyl group, provides the essential radiopacity required for modern diagnostic imaging agents. This product is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers specializing in non-ionic, low-osmolar contrast agents for enhanced patient safety and diagnostic clarity.

Application

• Key Intermediate for X-ray Contrast Media: Serves as a fundamental building block in the synthesis of iopamidol, iohexol, and other non-ionic contrast agents.
• Pharmaceutical Research & Development: Used in the discovery and development of new iodinated diagnostic compounds for computed tomography (CT) and angiography.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce high radiodensity into complex organic molecules.
• Contrast Agent Manufacturing: Integral to the commercial-scale production of injectable contrast media, ensuring batch-to-batch consistency and regulatory compliance.
• Academic & Industrial Research: Utilized in studies exploring novel applications of iodinated compounds in medical imaging and material science.

Basic Information

Product Name	5-(Carbamoyl)-2,4,6-Triiodoisophthalic Acid
CAS No.	79211-46-4
Molecular Formula	C9H4I3NO5
Molecular Weight	586.85 g/mol
Synonyms	5-Carbamoyl-2,4,6-triiodoisophthalic acid; 2,4,6-Triiodo-5-carbamoylisophthalic acid; 5-Carbamoyl-2,4,6-triiodo-1,3-benzenedicarboxylic acid; Triiodoisophthalic Acid Carboxamide Derivative; Iopamidol Intermediate; Iohexol Intermediate; CT Contrast Agent Intermediate; 79211-46-4
EINECS	Contact for details

Quality Control

Our 5-(Carbamoyl)-2,4,6-Triiodoisophthalic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, residual solvents, and heavy metals is provided with every shipment to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.