Description

(1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one CAS NO 79200-56-9 is a high-purity, chiral bicyclic lactam compound that serves as a critical advanced pharmaceutical intermediate. Its unique bridged structure makes it a versatile and valuable building block for the synthesis of complex, biologically active molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and fine chemical industries, particularly for creating novel drug candidates with specific stereochemical requirements.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of carbocyclic nucleoside analogues and other active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a precursor or scaffold in asymmetric catalysis and the construction of complex natural products.
• Medicinal Chemistry Research: Employed in drug discovery programs for the development of new antiviral, anticancer, or neurological agents.
• Process Chemistry: Serves as a starting material for the scalable, GMP-compliant production of target molecules.
• Fine Chemical Synthesis: Utilized in the preparation of specialty chemicals, agrochemicals, and other high-value compounds requiring precise stereochemistry.

Basic Information

Product Name	(1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one
CAS No.	79200-56-9
Molecular Formula	C6H7NO
Molecular Weight	109.13 g/mol
Synonyms	(1R,4S)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one; (-)-2-Azabicyclo[2.2.1]hept-5-en-3-one; (1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one; 2-Azabicyclo[2.2.1]hept-5-en-3-one, (1R,4S)-; (1R,4S)-2-Azanorborn-5-en-3-one; Bicyclic Lactam Intermediate; Chiral Azabicyclic Lactam
EINECS	Contact for details

Quality Control

Our (1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.