Description

Cbz-Dl-Homoserine is a protected derivative of the non-proteinogenic amino acid homoserine, featuring a carboxybenzyl (Cbz) protecting group on the amine functionality. This compound is a crucial building block in synthetic organic and medicinal chemistry, enabling the controlled synthesis of complex peptides and bioactive molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected amino acid precursor in solid-phase and solution-phase peptide synthesis (SPPS).
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Research: Employed in the study of enzyme mechanisms and the preparation of enzyme inhibitors or substrates.
• Agrochemical Development: Acts as an intermediate in the synthesis of specialized amino acid-based plant growth regulators or herbicides.
• Academic Research: A valuable reagent for universities and R&D institutions exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	Cbz-Dl-Homoserine
CAS No.	79074-03-6
Molecular Formula	C12H15NO5
Molecular Weight	253.25 g/mol
Synonyms	N-Carbobenzoxy-DL-homoserine; Benzyl N-(3-hydroxy-1-carboxypropyl)carbamate; DL-Homoserine, N-[(phenylmethoxy)carbonyl]-; N-Cbz-DL-homoserine; Z-DL-Homoserine; (RS)-2-[[(Benzyloxy)carbonyl]amino]-4-hydroxybutanoic acid; NSC 334884; CBZ-HOMOSERINE
EINECS	Contact for details

Quality Control

Our Cbz-Dl-Homoserine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.