Description

n-Boc-(2S,3S)-2-Amino-3-Benzyloxy-1-Butanol is a protected amino alcohol derivative, serving as a crucial chiral building block in advanced organic synthesis. Its value lies in the stereochemical integrity of its dual chiral centers, which is essential for constructing complex molecules with high enantiomeric purity. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the synthesis of active pharmaceutical ingredients (APIs), peptide mimetics, and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel therapeutic agents, including protease inhibitors and other small molecule drugs.
• Peptidomimetic Synthesis: Used to introduce stereodefined amino alcohol motifs into peptide backbones to enhance stability and bioavailability.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Custom Synthesis & Contract Manufacturing: Employed in the production of custom-designed molecules for research and commercial scale-up.
• Academic & Industrial Research: A valuable reagent for methodological development in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	n-Boc-(2S,3S)-2-Amino-3-Benzyloxy-1-Butanol
CAS No.	79069-63-9
Molecular Formula	C₁₆H₂₅NO₄
Molecular Weight	295.37 g/mol
Synonyms	(2S,3S)-2-[(tert-Butoxycarbonyl)amino]-3-(benzyloxy)butan-1-ol; 1-Butanol, 2-amino-3-(benzyloxy)-, N-BOC-, (2S,3S)-; tert-Butyl (1S,2S)-1-(benzyloxymethyl)-2-hydroxypropylcarbamate; (2S,3S)-2-(Boc-amino)-3-benzyloxy-1-butanol; Boc-(2S,3S)-Amino Benzyloxy Butanol; N-Boc-L-threoninol benzyl ether; (2S,3S)-2-((tert-Butoxycarbonyl)amino)-3-(benzyloxy)butyl alcohol
EINECS	Contact for details

Quality Control

Our n-Boc-(2S,3S)-2-Amino-3-Benzyloxy-1-Butanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.