Description

Diethylstilbestrol-3,4-Oxide is a specific epoxide derivative of the synthetic estrogen diethylstilbestrol (DES). This compound is of significant interest in pharmaceutical research and development, particularly for studying metabolic pathways and reactive intermediates. It serves as a critical reference standard and synthetic building block for researchers in medicinal chemistry, toxicology, and endocrinology who are investigating estrogen-related biological activities and mechanisms.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of diethylstilbestrol metabolites in research and quality control laboratories.
• Medicinal Chemistry Research: Acts as a key synthetic intermediate or model compound in the study of estrogen receptor interactions and the development of novel therapeutic agents.
• Toxicological Studies: Employed in metabolic and carcinogenicity research to understand the bioactivation and detoxification pathways of synthetic estrogens.
• Biochemical Research: Utilized in enzymatic studies, particularly those involving epoxide hydrolases and cytochrome P450 systems, to investigate metabolic transformations.
• Academic Research: Serves as a reagent in university and institutional labs for advanced studies in organic synthesis, hormone biology, and chemical toxicology.

Basic Information

Product Name	Diethylstilbestrol-3,4-Oxide
CAS No.	78969-61-6
Molecular Formula	C18H18O2
Molecular Weight	266.33 g/mol
Synonyms	DES-3,4-Oxide; Diethylstilbestrol 3,4-Epoxide; 4,4'-(1,2-Epoxyethylidene)bisphenol; (E)-4,4'-(1,2-Epoxyethene-1,2-diyl)diphenol; 3,4-Epoxy-α,α'-diethyl-4,4'-stilbenediol; α,α'-Diethyl-4,4'-stilbenediol 3,4-epoxide; Stilbestrol 3,4-oxide
EINECS	Contact for details

Quality Control

Our Diethylstilbestrol-3,4-Oxide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets the exacting standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.