Description

Glutamine-8 β-Endorphin is a synthetic peptide analog of the endogenous neuropeptide β-endorphin, specifically modified at the glutamine-8 position. This compound is of significant interest for its potential role in modulating opioid receptor activity and related physiological pathways. It serves as a critical research tool for neuroscientists, pharmacologists, and biochemists investigating pain mechanisms, neuropsychiatric disorders, and peptide hormone function. The product is supplied to support advanced research and development in pharmaceutical and life science sectors.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies of opioid receptor binding, signaling, and neuro-modulation.
• Pharmacological Studies: Employed in vitro and in vivo to investigate analgesic pathways, tolerance, and dependence mechanisms related to endorphin systems.
• Biochemical Assay Development: Serves as a key component in developing and validating assays for detecting and quantifying β-endorphin activity.
• Drug Discovery: Acts as a lead compound or molecular template for the design and synthesis of novel analgesic or neuroprotective agents.
• Academic & Institutional Research: Supports fundamental research into stress response, mood regulation, and reward circuits within the central nervous system.
• Peptide Chemistry Reference: Used as a standard in analytical methods such as HPLC and mass spectrometry for peptide identification and purity assessment.

Basic Information

Item	Detail
Product Name	Glutamine-8 β-Endorphin
CAS No.	78966-55-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	β-Endorphin (Glutamine-8); [Gln8]-β-Endorphin; β-Endorphin, 8-Glutamine; H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Gln-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu-OH; Gln8-β-Endorphin; β-Lipotropin (61-91), 8-glutamine; Synthetic β-Endorphin analog
EINECS	Contact for details

Quality Control

Every batch of Glutamine-8 β-Endorphin is manufactured and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.