Description

(S)-1-Benzyl-5-Oxopyrrolidine-2-Carboxylic Acid CAS NO 78964-11-1 is a high-purity chiral intermediate belonging to the class of N-substituted pyrrolidinone carboxylic acids. This compound is of significant value in the synthesis of complex pharmaceutical molecules, particularly those targeting neurological and metabolic disorders, due to its rigid proline-like scaffold and defined stereochemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of new active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, especially protease inhibitors and neuroactive compounds.
• Peptidomimetics Research: Used to construct constrained peptide analogs, enhancing metabolic stability and biological activity in medicinal chemistry programs.
• Asymmetric Synthesis: Serves as a precursor or catalyst ligand in stereoselective chemical transformations.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.
• Academic & R&D: Utilized in university and corporate research laboratories for investigating new synthetic methodologies and biological pathways.

Basic Information

Product Name	(S)-1-Benzyl-5-Oxopyrrolidine-2-Carboxylic Acid
CAS No.	78964-11-1
Molecular Formula	C13H15NO3
Molecular Weight	233.26 g/mol
Synonyms	(S)-1-Benzyl-5-oxopyrrolidine-2-carboxylic acid; (S)-1-Benzylpyrrolidine-2,5-dione-2-carboxylic acid; L-1-Benzyl-5-oxopyrrolidine-2-carboxylic acid; (2S)-1-Benzyl-5-oxopyrrolidine-2-carboxylic acid; 1-Benzyl-L-proline-5-carboxylic acid lactam; (S)-(-)-1-Benzyl-2-pyrrolidone-5-carboxylic acid; 78964-11-1; (S)-1-Bn-5-oxo-pyrrolidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our (S)-1-Benzyl-5-Oxopyrrolidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.