Description

n-Phenyl-2-[3-(Trifluoromethyl)Phenoxy]Pyridine-3-Carboxamide is a high-value, fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring a trifluoromethylphenoxy group, is engineered to impart unique physicochemical properties, making it indispensable for developing novel compounds with enhanced stability and bioactivity. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science: Serves as a monomer or additive for creating specialty polymers and liquid crystals with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and as a scaffold for constructing complex heterocyclic compounds in medicinal chemistry.
• Chemical Biology Probe Development: Utilized to create labeled compounds or inhibitors for studying biological pathways and protein functions.

Basic Information

Product Name	n-Phenyl-2-[3-(Trifluoromethyl)Phenoxy]Pyridine-3-Carboxamide
CAS No.	78863-62-4
Molecular Formula	C19H13F3N2O2
Molecular Weight	358.32 g/mol
Synonyms	2-[3-(Trifluoromethyl)phenoxy]-N-phenylnicotinamide; 2-(3-Trifluoromethylphenoxy)-N-phenyl-3-pyridinecarboxamide; N-Phenyl-2-(3-trifluoromethylphenoxy)nicotinamide; 3-Pyridinecarboxamide, 2-[3-(trifluoromethyl)phenoxy]-N-phenyl-; 78863-62-4; PF-05105679 (research code); 2-(α,α,α-Trifluoro-m-tolyloxy)-N-phenylnicotinamide
EINECS	Contact for details

Quality Control

Our production of n-Phenyl-2-[3-(Trifluoromethyl)Phenoxy]Pyridine-3-Carboxamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.